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Casa Grande

About Us

Casa Grande, located in Knoxville, IA, is your go-to destination for authentic Mexican cuisine bursting with flavor. We are committed to using the freshest ingredients to craft dishes of exceptional quality. Our vibrant atmosphere complements our diverse menu, which includes delectable fajitas, burritos, tacos, seafood platters, and chimichangas, paired with our signature margaritas. Enjoy our full-service bar and event room, perfect for hosting special occasions. Serving Des Moines, Pella, Grinnell, Urbandale, and Ankeny, IA, we invite you to savor the delightful offerings at Casa Grande. Visit us today!

Our Story

Casa Grande is a vibrant Mexican Restaurant located in Knoxville, IA. As a leading establishment in the local culinary scene, we take pride in providing our customers with an exceptional dining experience. With our extensive menu boasting a wide variety of authentic Mexican dishes, we strive to exceed your expectations with every bite.

At Casa Grande, we specialize in traditional Mexican cuisine, offering a diverse selection of A La Carte favorites. Our birria, tacos, tortas, soups, salads, enchiladas, chimichangas, burritos, steaks, pork dishes, chicken dishes, fajitas, seafood platters, and street tacos are expertly crafted using only the freshest ingredients and traditional cooking techniques. Each dish is a culinary masterpiece, bursting with flavors that transport you straight to the streets of Mexico.

To complete your dining experience, Casa Grande also offers a comprehensive beverage menu. Cool down and relax with our refreshing margaritas, perfectly mixed to your liking. We also offer a wide selection of beers, including draft beer, as well as an assortment of spirits and liquors to complement your meal.

Whether you're looking for a cozy dinner date or a fun family outing, Casa Grande welcomes you with open arms. Our comfortable and inviting atmosphere provides the ideal setting for any occasion. Enjoy our friendly and attentive service as we cater to your every need, making sure that your visit is nothing short of exceptional.

To accommodate different preferences and lifestyles, Casa Grande offers a range of service options. Dine-in and savor the warm ambiance and delicious aromas that fill our restaurant. If you're on the go, our convenient take-out service ensures that you can enjoy our delectable dishes wherever you choose. For those who prefer to dine at home, our prompt and efficient delivery service brings the taste of Mexico right to your doorstep.

We understand that celebrating special moments with loved ones is important, which is why Casa Grande also offers a party room for hosting private events. Whether it's a birthday party, family reunion, or corporate gathering, our dedicated staff will ensure that your event is a memorable one, complete with fantastic food and great ambiance.

At Casa Grande, we believe that everyone should be able to enjoy the flavors of Mexico, regardless of age. That's why we have designed a special kids' menu featuring tasty and wholesome options that are sure to put a smile on your little one's face.

To cater to different appetites and budgets, Casa Grande also offers enticing lunch specials, making it the perfect spot for a quick and satisfying midday meal.

With its expansive menu, excellent service, and inviting atmosphere, Casa Grande is the go-to destination for Mexican cuisine in Knoxville, IA. Come and join us today, and let us take you on a culinary journey that will leave you craving for more.

Areas Served

Knoxville, IA | Des Moines, IA | Pella, IA | Grinnell, IA | Urbandale, IA | Ankeny, IA | West Des Moines, IA

Languages Spoken

What We Offer

Our Specialties include:

Our Services include:

Our Brands include:

Our Products include:

Testimonials

On 10/22/2026 Lynne Chapman Chapman had this to say:
Delicious! Our server was very attentive and pleasant! Highly recommend!

On 7/3/2026 sith trooper had this to say:
It was lovely

On 5/11/2026 David Joiner had this to say:
Went here for Mother’s Day, the whole restaurant was filled with decorations and balloons wishing all the moms a happy Mother’s Day. Very nice ambiance for the occasion. We arrived 25 mins before closing and they seated us without issue. The food was incredible! And they even brought out a free desert for my wife. We love this place and will be back for sure!

On 5/5/2026 Amanda MacDonald had this to say:
Fast good food i perfer it over the other Mexican restaurants in town

On 3/24/2026 Sherry Turner had this to say:
Love this place

Contact Us

Casa Grande
110 E Main St Knoxville, IA 50138
Phone: (641) 842-3800
Fax: (515) 255-7050
Email: carmelosantos717@gmail.com

Where To Find Us

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Payment Types Accepted

American Express, Apple Pay, Debit Cards, Discover, MasterCard, Visa

Our Hours

Holiday Hours May Vary. Please Call For Details.

Monday: 11:00 AM - 9:00 PM
Tuesday: 11:00 AM - 9:00 PM
Wednesday: 11:00 AM - 9:00 PM
Thursday: 11:00 AM - 9:00 PM
Friday: 11:00 AM - 10:00 PM
Saturday: 11:00 AM - 10:00 PM
Sunday: 11:00 AM - 8:30 PM

News

As the days get cooler, there's no better time to gather around the table with family and friends. Enjoy all your Mexican favorites, refreshing beverages, and the warm hospitality that keeps guests coming back to Casa Grande.

Whether you're stopping in for a quick bite or a relaxing evening out, we're here to make every visit memorable.

📞 Bring your appetite and join us today!

#CasaGrandeIowa #FallDining #MexicanCuisine #FamilyFavorites #FoodAndFriends #LocalRestaurant #FreshFlavors #CommunityFavorite 🌮🍂🍹

Whether you're meeting friends for lunch, gathering the family for dinner, or celebrating a special occasion, Casa Grande is the perfect place to enjoy authentic Mexican cuisine. From flavorful favorites to refreshing drinks, every meal is made to bring people together.

Skip the cooking and join us for great food, friendly service, and a welcoming atmosphere!

📍 We look forward to serving you.

#CasaGrandeIowa #MexicanRestaurant #FamilyDining #AuthenticMexicanFood #LocalFavorite #LunchPlans #DinnerTime #SupportLocal

As the temperatures start to cool down, warm up with one of our delicious soups at Casa Grande. There's nothing better than a comforting bowl of homemade flavor paired with your favorite Mexican meal on a crisp fall day.

Whether you're stopping in for lunch or dinner, we've got the perfect way to take the chill off this season.

📍 Join us for a warm, satisfying meal today!

#SoupSeason #ComfortFood #CasaGrandeIowa #FallFlavors #WarmUpWithUs #MexicanCuisine #FreshMade #LocalFavorite

It's the most spooktacular time of the year at Casa Grande! Our famous Spooky Margaritas have returned and are available every weekend throughout October. These festive favorites have become an annual tradition, bringing a fun Halloween twist to your favorite margarita.

Gather your friends, enjoy authentic Mexican cuisine, and sip on a spooky creation before they're gone!

🎃 Available weekends only in October!

#SpookyMargaritas #CasaGrandeIowa #HalloweenDrinks #OctoberSpecials #WeekendVibes #MargaritaSeason #CasaGrande

🍂🌮 Welcome September with Flavor at Casa Grande! 🌮🍂

As the days start to cool down, it's the perfect time to gather with family and friends over a delicious meal. At Casa Grande, you'll find authentic Mexican favorites made with fresh ingredients, from sizzling fajitas and flavorful tacos to hearty burritos and refreshing margaritas. Whether you're celebrating a special occasion or simply enjoying a night out, our welcoming atmosphere is ready for you.

✅ Authentic Mexican Cuisine
✅ Fresh, Flavorful Ingredients
✅ Full-Service Bar & Margaritas
✅ Family-Friendly Dining
✅ Perfect for Lunch, Dinner & Gatherings

Make September a little more delicious. Stop by Casa Grande and enjoy the flavors everyone is talking about! 🌶️🍹

#CasaGrande #SeptemberDining #MexicanFood #KnoxvilleIA #Fajitas #Tacos #Margaritas #FamilyDining #LocalRestaurant #AuthenticFlavors

Info

Drinks + Lunch Menu

FAQ

What type of cuisine does Casa Grande serve?
Casa Grande specializes in authentic Mexican cuisine, offering a variety of dishes such as tacos, enchiladas, burritos, fajitas, and house specialties made with fresh ingredients.
Do you offer takeout or delivery?
Yes! Casa Grande typically offers takeout services. Delivery may be available through local food delivery platforms - check with the restaurant directly or visit our website for options.
Are vegetarian or gluten-free options available?
Yes, many Mexican dishes can be customized to accommodate dietary preferences. Casa Grande likely offers vegetarian options and may be able to adjust meals for gluten-free needs upon request.
Can I host a party or event at Casa Grande?
Casa Grande may offer space for small gatherings or special events. Contact the restaurant to inquire about group reservations, catering options, or private dining availability.
What are your hours of operation?
We are open 7 days a week; Monday through Thursday 11am - 9pm, Friday & Saturday 11am - 10pm, and Sunday 11am - 8:30pm. Hours may vary by location and day of the week. It’s best to check Casa Grande’s website or call the restaurant directly for the most accurate and up-to-date schedule.

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